MiR-146a G/C rs2910164 variation in South African Indian and Caucasian patients with psoriatic arthritis
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Author’s response to reviews Title: MiR-146a G/C rs2910164 variations in South African Indian and Caucasian patients with psoriatic arthritis Authors:
Authors: Ajesh Maharaj ([email protected]) Pragalathan Naidoo ([email protected]) Terisha Ghazi ([email protected]) Naeem Abdul ([email protected]) Shanel Dhani ([email protected]) Taskeen Docrat ([email protected]) Prithiksha Ramkaran ([email protected]) Paul Tak ([email protected]) Niek de Vries ([email protected]) Anil Chuturgoon (chutur...
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Background & Aims: Behcet's disease (BD) is an autoimmune disease that usually occurs with oral, genital and ocular ulcers. The cause of this disease is unknown and environmental, genetic and immunological factors contribute to its development. In the present study, the relation between rs2910164 and rs57095329 polymorphisms of miR146a gene with the potential for BD was investigated in Iranian ...
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Background and Aim: Several investigations have evaluated the association of miR-146a rs2910164 and miR-27a rs895819 single-nucleotide polymorphisms with susceptibility to type 2 diabetes (T2D). However, the findings are conflicting and inconclusive. Therefore, this meta-analysis performed to investigate the association between these polymorphisms and T2D risk. Methods: Studies were identifie...
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miR-146a plays important roles in cancer as it directly targets NUMB, an inhibitor of Notch signaling. miR-146a is reportedly regulated by a G>C polymorphism (SNP; rs2910164). This polymorphism affects various cancers, including colorectal cancer (CRC). However, the clinical significance of miR-146a polymorphism in CRC remains unclear. A total of 59 patients with CRC were divided into 2 groups:...
متن کاملAssociation of pre-miR-146a rs2910164 polymorphism with the risk of head and neck cancer.
BACKGROUND Over- or underexpression of miR-146a has been reported in several different human tumor types, and a polymorphism in its precursor form (pre-miR-146a rs2910164 G/C) has been recently studied in connection with cancer susceptibility. The aim of the present study was to investigate the possible influence of the pre-miR-146a rs2910164 polymorphism on the risk of squamous cell carcinoma ...
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ژورنال
عنوان ژورنال: BMC Medical Genetics
سال: 2018
ISSN: 1471-2350
DOI: 10.1186/s12881-018-0565-1